94 chevy 1500

my 94 chevy 1500 with a 350 runs 100% better when i disconect the wire under the dash for setting the timeing i have set the timeing to o btd but it runs bad and i get a little spark knock im thinking the pick up in the
distibuter is going bad but not sure how can i test it and if i have to use a scope should i get a square wave form i dont think it is the knock senser and i have tried the timeing in many different ways up to 15. will it hurt anything to drive with the wire disconected till i fix the problem. thanks for any ideas
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