The time it takes for "rust" or oxidation to form is dependent upon (1) the dissimilarity of the two metals in contact -- dissimilarity in the scale of noblest to least noble metal, i.e., the further apart in the scale the two metals are, the more galvanic action; and (2) the solution the two metals are "immersed" in, e.g., saltwater really speeding up the process.
Anti-seize compound is made up of aluminum powder/paste, i.e., quite conductive, but may, in itself, be the sacrificial "anode" between two other dissimilar metals.
Anti-seize' main purpose is not to halt or slow down rusting/oxidation, although it may do just that depending upon the situation -- its main purpose is to... TADA!!! prevent seizing of parts. It can be used successfully and without downstream issues on head bolts, starter bolts, intake/exhaust manifold bolts/studs, exhaust flanges, mating exhaust pipes/mufflers, (not on any internal engine component, all external applications, especially if exposed to the elements), and lug nuts.
The key to using on any torque value-sensitive task is (A) cleanliness of the mating parts PRIOR to conservative application of the anti-seize compound (the micro-welds between the mating parts are decreased somewhat but not enough to affect holding capacity while the surface imperfections are filled in by the very soft aluminum powder -- end result is no galling during tightening or loosening); and (B) torquing gradually to spec, then retorquing after a certain period of time or use.
Worst thing to use on closed/capped lug nuts is grease -- ask any Porsche purist...
Franko
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