Well, there seems to be no consistency to it. I can't reproduce the condition on command.
Just say I'm driving down the road and giving it enough gas to put a load on the drivetrain. Sometimes when I let off, I get the noise and vibration. It literally sounds like someone dropping a few machine screws into a set of turning gears. It's loud, and there's a good deal of vibration. The whole event starts and ends in less than a second. It's a very short but noticeable burst of noise and vibration.
I tried to make it happen yesterday... going from acceleration to letting off completely, sometimes slamming the brakes. Tried accelerating and letting off in the middle of a curve at different speeds, sometimes braking as well--no luck.
Also, I didn't mention, when putting it in gear, or going from reverse to drive or vice versa, there's a pretty loud bang. Me and a buddy took turns watching the driveshaft while changing gears in his driveway. You could see it move and then stop violently. Also, if you're driving with the drivetrain under load, and release the gas suddenly, you hear a slight bang...more like a loud thump. And then it happens again if you give it gas while coasting if the drivetrain is NOT under load. You gotta ease back into the gas to keep that from happening. It sucks when you're on the interstate and some idiot hits the brakes at 80mph. You suddenly let off the gas and BANG!
It just seems there's always been a good deal of slack in the drivetrain--at least as long as I've owned the truck (since September of 2002).
-JP