2000 Durango, would this be a drive shaft issue?

I have a 2000 durango with 102,000 miles on it. When accelerating slowly a squeaking noise is heard, when foot off pedal, sound goes away. At freeway
speeds, the noise also a noise that seems to be a low tone (bass) fast repetion viberation when the pedal is pressed down and it goes away when pedal is released. Sounds like noise from deep tread on tires/road noise, but is consistent no mattter the pavement. Occurs at speeds greater than 45mph.
Dealership did a test drive with me and said he thought was the drive shaft. This does not make sense to me, could he be right?
Mr.
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It could be bad U joints, does it make any big clunking when doing from drive to reverse
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No noises when shifting from drive to reverse, while vehicle is stopped. Don't think I dare attempt the shifting while moving... :)

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