The RPM of the engine drives the AC compressor. When in Drive, the RPM
of the engine is higher than when in Overdrive, therefore the compressor
also cycles a little faster. You might check the drive belt for the
compressor to be sure it is within specification for belt
deflection....IOW, being tight enough. Also it may be a good idea to
check the AC systems' refrigerant charge.
Hope this is of some use.......
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