Hi,
I have added 12k miles to my '00 E320 and really love the car.
the only thing which bugs me why the suspension takes speed bumps so badly. one need to slow down to walking speed in order to ride over them which all car being shake. I have not noted it in any other car I drove before.
on the positive side though - when riding at high speeds - it seems to be perfectly tuned. all road irregularities, smaller bumps and potholes are soaked in and besides interesting sound effects there is merely felt inside the car.
I know you can not have everything as far as suspension is concerned - but still I would expect it takes speed bump a bit better.
Andy