Just had an AC Delco taught air-conditioning service class a few weeks ago, which had some mention of vehicle cooling systems also....
THEY say: With green coolant flush every two years, or 24,000mi. With Dex-Cool flush every five years or 150,000mi. If DEX-Cool is in ANY way compromised, resort to the green schedule.
They of course also said a whole lot about A/C service, but that's not why I posted...lol
GW