Unless you are burning the cheapest fuel you can find, I doubt if your injectors are clogged. A can of fuel injector cleaner won't hurt if you follow the directions carefully. The only way to tell if an injector is working properly (spray pattern, volume, and closing) is to remove it and use a bench checker.
As qslm suggested earlier, you may want to check which cylinder is misfiring with an OBD II code reader, clear the codes, and then swap coils with another cylinder that is working properly and see if the problem moves to the cylinder you swapped with.