I have a 2004 LS 430. The car's Bluetooth system doesn't allow telephone numbers to be manually entered for outgoing calls when the car is moving. The number buttons on the screen "gray out."
I note that there's a way to override the navigation system so as to allow destination addresses to be input while the car is in motion:
Geoff
-- "The libido is life's fuel gauge."
-- Sam Sacks, _Commentary_, Jan. 2010