FYI I put Tufoil in a Dodge slant 6 once, in the 70's. It slowly increased in idle until I was afraid to put it in drive. Had to learn to adjust the idle. It didn't do that in Dodge V8's. In some cars it lowers the temp. by 10 degrees. The Nissan isn't affected.
I got 21 mpg overall in the slant 6 (1/2 ton van). I was also using W6, a fuel additive I can't find anymore (it would take the smell out of diesels and give trucks an extra gear on hills, if their radiators could handle it, for 1 cent to treat a gallon, in the '70s - no company fleets would talk about it for fear of losing their fuel in the shortage), and a "ramjet" blowby carbureting device. I may have been using a Cagle, which auto-adjusted the fuel pressure by vaccuum in case of a float valve that wasn't real effective (going rich). Now I remember that I put in a flex-fan too.
I no longer have vans, but in my '86 Dodge 318 carbureted I put in one of those "Tornados" that spins up the intake air to help atomize the fuel. I felt more power right away, so I could give it less gas. Nothing massive but it was a change.
I've been considering trying a Tornado in the Nissan, but I don't know if the air will still be spinning much by the time it gets to the injectors, which seem to be in very narrow passages some way away from where the Tornado would go into the duct.