Advice on Spark Plug R&R 460 in F250?

I can't imagine there is such a diagram...If it looks like such a big job I'd suggest you bring your truck in for a complete tune-up by a competent mechanic.

If you have your mechanic replace with a good sparkplug, you'll most likely never have to replace them again.

I agree. Before unleaded gas, replacing spark plugs was commonplace. Since unleaded gas, I have never had to replace one, period. Technology has a way of solving problems sometimes, like radials vs snowtires.

Chuck, this is the kind of work where you look at the situation and figure out which tools in your box will get the job done. Sometimes you work from below or even from the wheel wells. Get warmed up by starting with the easiest ones and before you know it you will be done.

There ya go...