Blimey, came across this thread after a lot of water under the bridge.
I have a 110 V8 hard-top from 1988. Santana box. It has a removable rectangular cross-section (don't they all), but have never had to remove it as took the box out from the top. If you remove the engine first then you can take off the bell housing and then the whole gearbox and transfer box will come out of the passenger door - did it on my own, but a spare set of hands always helps.
I fitted a tubular manifold from Rimmer when I put it all back together, and it was tight on the driver-side. Needed a bit of tweaking, though I later did some tuning on the manifold face and a few thou there makes for a few tenths as it passes the chassis.
One difference between the V8 and the four pot is the swivel hubs have negative camber. I had a 110 TD and the 110 V8 for a couple of years (both the same age) and kept wondering why the V8 looked bandy. It turns out there is no camber on the normal 110, but one and half degrees on the V8. It is an easy way to spot a genuine V8.
The Santana box is strong, but a bit of a truck box (slow changes). The LT77 only came good later on (D suffix onwards when the beefed up the bearings). I have had two of the earlier ones die on me (one in a TD110, the other in a P6 Rover) and am not very impressed (but I have a G suffix box in a 4.5 litre Marcos and its still there after 60k miles, so the very late ones are pretty good - but rare). Rpi reckon the R380 box is the way to go, and if it has an LT77 sweetness to the change and Santana box strength then that would be the right choice IMHO. Rpi say it is a straight swap, so mounting should be the same. Main difference is that reverse moves opposite 5th (but you won't get it in reverse if looking for a 6th gear at speed!)
Phone 'em up and ask..
Steve