There is simply too much obfuscation so, I'm starting with a clean slate. What I hear Leon saying is that at any given velocity of a car, lets say a Miata for interest of this group, the power output from the engine is the same, assuming all other external factors are the same (e.g., engine modifications don't change the profile and thus the drag of the car). Also, assuming similar fuel mixture in the combustion chamber (which is controlled by the ECU to meet exhaust and performance criteria), the amount of air entering through the intake system stays the same (e.g., same power, same fuel to air ratio, and therefore same air volume). Thus, the throttle plate in the air intake will be further closed in a less restrictive air intake system compared to stock.
Now for the difficult part. I believe Leon is stating that at constant power output, the engine with the less restrictive intake system will need to work harder to pull in the air due to lower vacuum needed to pull the same volume across the trottle plate. Put another way, more fuel is needed to the same net power output to the wheels since more power is used to pull air into the enginer. If this is the case, then I can understand Leon's argument. For maximum fuel efficiency, the intake system should be designed to minimize pumping losses at the designed optimum speed.
What I don't understand, is why moving restriction from the intake system to the throttle plate results in the engine having more pumping losses. I understand that the pressure loss across the throttle plate will increase, but at the same time, the pressure loss across the rest of the system is less. Therefore, couldn't the vacuum down stream of the throttle plate to be the same in both cases. Why isn't it the other way around where the restriction across the throttle plate actually results in less total pressure drop than the restricted intake system?
Now, of course, this entire argument is only valid for the steady state case (e.g., the car at constant velocity and the engine at constant power output). From my experience, even at what appears to be constant velocity (e.g., driving on the highway at say 65 miles per hour), the engine output varies to adjust for other factors (e.g., incline of the road, wind, passing cars, etc.). Average fuel consumption is thus the average overtime as the engine output and thus fuel efficiency vary to maintain constant speed.
Gus