Nope. I've installed three over the years. 80 2wd Toyota, 86 Ford Ranger Super Cab 4x4 and 88 Suzuki Samurai. All of them went in pretty simply and never gave me any trouble the whole time I used them.
Be careful when you install one though. Follow the instructions closely and ensure anything that is connected to both the body and frame either has enough slack/adjustment or you have a bracket to cure the problem.
Matt
99 V-10 Super Duty, Super Cab 4x4