Let's hypothesize that all foreign car companies have gone in the tank, (or that the US has embargoed all foreign cars, including those made in the US) and going further, all foreign cars have been confiscated by the US government. Now, since we all drive, and need transportation, we're forced to buy American iron. The question is - which of the big three would you choose, and within their product lines, which model would you choose to buy? Keep in mind that nobody's suddenly gotten rich, so your purchase must be within your budget...no Escalades or Navigators unless you can afford them.
In my own case, and based only on my experiences with American cars, I think I'd go with a Ford product, since they've been less troublesome to me and my wallet, and probably either a Mercury Milan or perhaps a Ford Minivan. If I had to choose GM, it'd likely be a midsize Buick, because they seem to get good gas mileage (better than I'd have imagined). Or perhaps a Chevrolet sedan. No Pontiacs or Cadillacs. Chrysler products seem to have more breakdowns and they are largely ugly to my view, although the Town and Country minivan seems pleasant enough.